The TBC1D4 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to AS160, and TBC1D4. This antibody recognizes Human antigen. The TBC1D4 Antibody has been validated for the following applications: ELISA, and Immunohistochemistry.
Description
TBC1D4 Antibody: TBC1D4, also known as the Akt substrate AS160, was initially identified as an Akt substrate containing a GTPase-activating domain that regulates GLUT4 trafficking, with activation following insulin stimulation. TBC1D4 truncations in humans is a major cause of dominant inherited insulin resistance. The loss of TBC1D4 results in the accumulation of GLUT4 in compartments that are primed for fusion in basal adipocytes